We hypothesize that the excess GSSG in cytosol were transported to extracellular space where class III peroxidases locate and served as the oxidant either directly or indirectly during ROS production by class III peroxidases (Figure 6)
Pallav Sengupta, orcid.org/0000-0002-1928-5048 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The common principle of peroxidatic cysteine or selenocysteine residues
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Thus, the significant increase in levels of 3-NT observed in the autism cerebellum and BA22 was not unexpected and is consistent with elevated superoxide production and aconitase inactivation
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